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Cruises from San Diego in 2025

Explore Cruises from San Diego in 2025

An extraordinary expedition from the sunny shores of San Diego in 2025, will set the stage for an array of unforgettable West Coast experiences. Begin your voyage where the vibrant city life of San Diego merges with the majestic Pacific, leading you to explore diverse coastlines and the mesmerizing landscapes of your destinations. Experience the perfect blend of Southern California's laid-back culture, awe-inspiring natural vistas, and the cutting-edge innovations that define the Pacific's edge.

78 Itineraries Found
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4 Nights | Pacific Coastal | Holland America | Zaandam

4 Nights | Pacific Coastal | Holland America | Zaandam
Lowest Rate*
  • Interior $419.00
  • Oceanview $519.00
  • Suite $769.00
From USD $419.00* USD $104.75 / night(s) Includes taxes and fees

4 Nights | Pacific Coastal | Holland America | Nieuw Amsterdam

4 Nights | Pacific Coastal | Holland America | Nieuw Amsterdam

Nieuw Amsterdam

San Diego Vancouver (Vancouver, BC)

4 Nights

San Diego | Victoria Airport (Victoria) | Vancouver (Vancouver, BC) **

Cruise Deals from San Diego to Vancouver (Vancouver, BC)

Lowest Rate*
  • Interior $484.00
  • Oceanview $584.00
  • Balcony $734.00
  • Suite $834.00
From USD $484.00* USD $121.00 / night(s) Includes taxes and fees

4 Nights | Pacific Coastal | Holland America | Koningsdam

4 Nights | Pacific Coastal | Holland America | Koningsdam

Koningsdam

San Diego San Diego

4 Nights

San Diego | Santa Barbara | AVLN | Ensenada | San Diego **

Cruise Deals from San Diego

Lowest Rate*
  • Interior $529.00
  • Oceanview $679.00
  • Balcony $779.00
  • Suite $1,179.00
From USD $529.00* USD $132.25 / night(s) Includes taxes and fees

7 Nights | Mexico | Holland America | Nieuw Amsterdam

7 Nights | Mexico | Holland America | Nieuw Amsterdam

Nieuw Amsterdam

San Diego San Diego

7 Nights

San Diego | Ensenada | Los Cabos | Puerto Vallarta | San Diego **

Cruise Deals from San Diego

Lowest Rate*
  • Interior $794.00
  • Oceanview $944.00
  • Balcony $1,194.00
  • Suite $2,294.00
From USD $794.00* USD $113.43 / night(s) Includes taxes and fees

7 Nights | Mexico | Holland America | Zaandam

7 Nights | Mexico | Holland America | Zaandam

Zaandam

San Diego San Diego

7 Nights

San Diego | La Paz | Loreto | Los Cabos | San Diego **

Cruise Deals from San Diego

Lowest Rate*
  • Interior $829.00
  • Oceanview $929.00
  • Suite $2,229.00
From USD $829.00* USD $118.43 / night(s) Includes taxes and fees

CruiseBooking.com is excited to present a wide array of cruise adventures departing from San Diego in 2025. Customize your journey to fulfill the vacation of your dreams, sailing through the Pacific to discover the stunning cruise destinations of the Pacific Coast, Mexico, Central America, and beyond. Our selection offers a variety of departure dates and cruise lengths designed to satisfy every type of traveler. Whether you're in search of a tranquil retreat, an action-packed adventure with friends, or an unforgettable family vacation, a cruise from San Diego offers the perfect mix of relaxation, discovery, and adventure.

Take this opportunity to dive into our carefully selected collection of cruises from San Diego and embark on the adventure of a lifetime. Your 2025 cruise from San Diego awaits—find it with CruiseBooking.com, and set sail on a journey replete with exploration, beauty, and magical experiences.

FAMOUS PORTS OF CALL FROM SAN DIEGO IN 2025

When the spirit of adventure sails along the Pacific breeze, you’ll be taken you from the laid-back California coast to the heart of the Pacific's treasures. Setting sail from this sun-drenched city offers an unparalleled journey through diverse cultures, stunning landscapes, and unforgettable experiences. Each port of call on your voyage from San Diego provides a distinct adventure into the beauty and allure of the Pacific and its many wonders.

Astoria

Dive into the rich history and natural beauty of Astoria, Oregon's oldest city, nestled at the mouth of the Columbia River. This picturesque port town is a gateway to the rugged Pacific Northwest, offering a mix of cultural museums, Victorian architecture, and the iconic Astoria Column, with panoramic views of the river and beyond. Explore the scenic beauty of the Oregon coast and its dense forests, a testament to the region's pioneering spirit.

Vancouver (BC)

Discover Vancouver, British Columbia, a cosmopolitan city surrounded by water and mountains. This vibrant city offers a blend of cultures, outdoor activities, and culinary experiences. Stroll through the bustling markets of Granville Island, explore the lush landscapes of Stanley Park, or enjoy the city's dynamic arts scene. Vancouver serves as a stunning introduction to Canada's natural beauty and urban sophistication.

Mazatlán

Visit Mazatlán, the "Pearl of the Pacific" in Mexico, known for its long sandy beaches, historic Old Town, and vibrant cultural life. This city combines the charm of its colonial architecture with the allure of its lively malecón and delicious seafood. Whether you're exploring the historic plazas and cathedrals or watching the cliff divers at Olas Altas, Mazatlán offers a rich and engaging experience.

Puerto Quetzal

Experience the gateway to Guatemala's rich culture and stunning landscapes at Puerto Quetzal. This port offers access to the ancient ruins of Tikal, the colonial beauty of Antigua, and the breathtaking Lake Atitlán. Guatemala's rich Mayan heritage, combined with its volcanic landscapes and colorful markets, makes for an unforgettable exploration.

Lautoka

Conclude your journey in Lautoka, known as Fiji's Sugar City, surrounded by sugarcane fields and the clear blue waters of the Pacific. Lautoka's heart beats in its vibrant markets, beautiful botanical gardens, and friendly locals. Beyond the city, Fiji's stunning beaches, coral reefs, and islands offer a paradise for snorkeling, diving, and immersing yourself in the island's laid-back lifestyle.

Setting sail from San Diego in 2025, this cruise invites you to explore the vast beauty and diversity of the Pacific. From the cultural tapestry of Vancouver to the tropical allure of Lautoka, each destination along the way promises its own unique adventures, cultural insights, and moments of awe. Embark on this voyage for an extraordinary exploration of the Pacific's most captivating destinations.

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Frequently Asked Questions about Cruises From San Diego in 2025

Absolutely, San Diego, known as the craft beer capital of America, has inspired several 2025 cruises to feature craft beer tastings and brewery tours. These cruises include visits to renowned breweries in port cities and onboard tastings led by expert brewers.

Yes, culinary cruises from San Diego in 2025 offer cooking workshops where you can learn to prepare local dishes under the guidance of expert chefs. These interactive classes often include market visits in port cities to source fresh ingredients, providing a deliciously immersive experience.

Photography-focused cruises from San Diego in 2025 are perfect for those looking to improve their skills. These cruises feature expert-led workshops, photo excursions in each port, and critiques to help you capture the stunning landscapes and vibrant cultures of the Pacific.

Yes, several cruise lines departing from San Diego in 2025 offer solo cabins or matching services to connect solo travelers with roommates, helping to avoid the single supplement while fostering new friendships.

Select cruises from San Diego offer the unique opportunity to explore underwater worlds in a real submarine. These excursions allow you to see marine life and sunken treasures up close, adding an unforgettable adventure to your cruise experience.

Cruises from San Diego in 2025 boast expansive wellness facilities, including salt therapy rooms, outdoor fitness parks, and meditation spaces with panoramic ocean views. Holistic wellness programs are designed to rejuvenate the body, mind, and spirit throughout your journey.
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