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  3. 21 Night Cruises

21 Night Cruises

Cruises for 21 Nights

Find the best 21-night cruise on your budget and book your unforgettable vacation today. Here you will find amazing 21-nights cruise trips around the year. Discover a wide selection of itineraries, ships, and cruise lines for your 21-nights getaway. Whether you seek a family cruise or an adult-only retreat, book now on CruiseBooking.com for an unforgettable experience.

440 Itineraries Found
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21 Nights | Southern Europe | MSC Cruises | MSC Grandiosa

21 Nights | Southern Europe | MSC Cruises | MSC Grandiosa
MSC Cruises

MSC Grandiosa

Rio De Janeiro Civitavecchia (Rome)

21 Nights
Rio De Janeiro | Buzios | Salvador | Maceio | Las Palmas | Arrecifes | TNG | Malaga | Valencia | Marseille | Genoa | Civitavecchia (Rome) **

Cruise Deals from Rio De Janeiro to Civitavecchia (Rome)

Lowest Rate*
  • Interior $1,290.92
  • Suite $5,180.92
From USD $1,290.92* USD $61.47 / night(s) Includes taxes and fees
What's Included?

21 Nights | Southern Europe | MSC Cruises | MSC Grandiosa

21 Nights | Southern Europe | MSC Cruises | MSC Grandiosa
MSC Cruises

MSC Grandiosa

Santos Genoa

21 Nights
Santos | Rio De Janeiro | Buzios | Salvador | Maceio | Las Palmas | Arrecifes | TNG | Malaga | Valencia | Marseille | Genoa **

Cruise Deals from Santos to Genoa

Lowest Rate*
  • Interior $1,290.92
  • Oceanview $1,780.92
  • Balcony $2,270.92
  • Suite $4,400.92
From USD $1,290.92* USD $61.47 / night(s) Includes taxes and fees
What's Included?

21 Nights | Transatlantic | MSC Cruises | MSC Divina

21 Nights | Transatlantic | MSC Cruises | MSC Divina
MSC Cruises

MSC Divina

Naples Miami

21 Nights
Naples | Civitavecchia (Rome) | Genoa | Marseille | Barcelona | Valencia | Alicante | Lisbon | Funchal | St. Johns | St Maarten (Philipsburg) | San Juan | Miami **

Cruise Deals from Naples to Miami

Lowest Rate*
  • Interior $1,430.92
  • Oceanview $1,720.92
  • Balcony $2,400.92
  • Suite $3,780.92
From USD $1,430.92* USD $68.14 / night(s) Includes taxes and fees
What's Included?

21 Nights | World Cruise | Princess | Island Princess

21 Nights | World Cruise | Princess | Island Princess
Princess

Island Princess

Sydney Cape Town

21 Nights
Sydney | Melbourne | Perth (Fremantle) | Port Louis | Cape Town **

Cruise Deals from Sydney to Cape Town

Lowest Rate*
  • Interior $1,435.51
  • Oceanview $1,783.51
  • Balcony $2,154.51
  • Suite $2,644.51
From USD $1,435.51* USD $68.36 / night(s) Includes taxes and fees
What's Included?

21 Nights | Caribbean | Costa Cruises | Costa Fascinosa

21 Nights | Caribbean | Costa Cruises | Costa Fascinosa
Costa Cruises

Costa Fascinosa

La Romana Marseille

21 Nights
La Romana | St Lucia (castries) | Barbados (Bridgetown) | Pointe a Pitre | St. Johns | Tortola | La Romana | St Maarten (Philipsburg) | Santa Cruz de Tenerife | Cadiz | Barcelona | Marseille **

Cruise Deals from La Romana to Marseille

Lowest Rate*
  • Interior $1,583.40
  • Oceanview $2,003.40
  • Balcony $2,473.40
  • Suite $2,783.40
From USD $1,583.40* USD $75.40 / night(s) Includes taxes and fees
What's Included?

FAQs for 21 Night Cruises

The cost of a 21-night cruise with a family can vary depending on various factors such as cruise line, destination, cabin type, and amenities. Prices can range from a few thousand dollars to several tens of thousands of dollars.

The benefits of doing a 21-nights cruise trip are extensive exploration, relaxation and entertainment, an all-inclusive experience, a family-friendly atmosphere, and unpack once and visit multiple destinations.

When it comes to destinations for a 21-night cruise, there are numerous options. However, one suggestion for an enjoyable 21-night cruise could be a Mediterranean itinerary. This region offers a diverse mix of historical sites, stunning landscapes, and vibrant cultures. You can visit iconic cities like Barcelona, Rome, Athens, and Istanbul, explore picturesque islands such as Santorini and Mykonos, and experience the charm of lesser-known ports. The Mediterranean provides a perfect blend of history, culture, and natural beauty that can make a 21-night cruise truly memorable.
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