Set sail with MSC World America
Find a cruise and book cruises direct - no booking fee!
  • Book Now
successmsg

errormsg


Need Multi Cabin? Click Here

21 Night Cruises

Cruises for 21 Nights

Find the best 21-night cruise on your budget and book your unforgettable vacation today. Here you will find amazing 21-nights cruise trips around the year. Discover a wide selection of itineraries, ships, and cruise lines for your 21-nights getaway. Whether you seek a family cruise or an adult-only retreat, book now on CruiseBooking.com for an unforgettable experience.

523 Itineraries Found
  • Filters:

21 Nights | Southern Europe | MSC Cruises | MSC Grandiosa

21 Nights | Southern Europe | MSC Cruises | MSC Grandiosa

MSC Grandiosa virtual-360

Santos Genoa

21 Nights

Santos | Rio De Janeiro | Buzios | Salvador | Maceio | Las Palmas | Lanzarote | TNG | Malaga | Valencia | Marseille | Genoa **

Cruise Deals from Santos to Genoa

Lowest Rate*
  • Interior $1,290.92
  • Oceanview $1,780.92
  • Balcony $2,270.92
  • Suite $5,380.92
From USD $1,290.92* USD $61.47 / night(s) Includes taxes and fees

21 Nights | Caribbean | Holland America | Zuiderdam

21 Nights | Caribbean | Holland America | Zuiderdam

Zuiderdam

Boston Miami

21 Nights

Boston | San Juan | St Thomas | St Maarten (Philipsburg) | St Lucia (castries) | Barbados (Bridgetown) | Willemstad | HAFC | Miami | Grand Turk | San Juan | St Thomas | HAFC | Miami **

Cruise Deals from Boston to Miami

Lowest Rate*
  • Interior $1,340.00
  • Oceanview $1,959.00
  • Balcony $2,600.00
  • Suite $4,272.00
From USD $1,340.00* USD $63.81 / night(s) Includes taxes and fees

21 Nights | Transatlantic | MSC Cruises | MSC Seaside

21 Nights | Transatlantic | MSC Cruises | MSC Seaside

MSC Seaside virtual-360

Livorno Miami

21 Nights

Livorno | Marseille | Barcelona | Valencia | Casablanca | Barbados (Bridgetown) | St George's | St Maarten (Philipsburg) | San Juan | Miami **

Cruise Deals from Livorno to Miami

Lowest Rate*
  • Interior $1,405.29
  • Oceanview $1,651.29
  • Balcony $1,898.29
  • Suite $3,266.29
From USD $1,405.29* USD $66.92 / night(s) Includes taxes and fees

21 Nights | Southern Europe | MSC Cruises | MSC Lirica

21 Nights | Southern Europe | MSC Cruises | MSC Lirica

MSC Lirica virtual-360

Venice Santos

21 Nights

Venice | Kerkyra | Syracuse (siracusa) | Palermo | Valencia | Santa Cruz de Tenerife | Recife | Buzios | Rio De Janeiro | Santos **

Cruise Deals from Venice to Santos

Lowest Rate*
  • Interior $1,412.92
  • Oceanview $1,712.92
  • Balcony $2,422.92
  • Suite $3,202.92
From USD $1,412.92* USD $67.28 / night(s) Includes taxes and fees

21 Nights | Southern Europe | MSC Cruises | MSC Grandiosa

21 Nights | Southern Europe | MSC Cruises | MSC Grandiosa

MSC Grandiosa virtual-360

Rio De Janeiro Civitavecchia (Rome)

21 Nights

Rio De Janeiro | Buzios | Salvador | Maceio | Las Palmas | Lanzarote | TNG | Malaga | Valencia | Marseille | Genoa | Civitavecchia (Rome) **

Cruise Deals from Rio De Janeiro to Civitavecchia (Rome)

Lowest Rate*
  • Interior $1,420.92
  • Oceanview $2,040.92
  • Balcony $2,300.92
  • Suite $8,610.92
From USD $1,420.92* USD $67.66 / night(s) Includes taxes and fees

FAQs for 21 Night Cruises

The cost of a 21-night cruise with a family can vary depending on various factors such as cruise line, destination, cabin type, and amenities. Prices can range from a few thousand dollars to several tens of thousands of dollars.

The benefits of doing a 21-nights cruise trip are extensive exploration, relaxation and entertainment, an all-inclusive experience, a family-friendly atmosphere, and unpack once and visit multiple destinations.

When it comes to destinations for a 21-night cruise, there are numerous options. However, one suggestion for an enjoyable 21-night cruise could be a Mediterranean itinerary. This region offers a diverse mix of historical sites, stunning landscapes, and vibrant cultures. You can visit iconic cities like Barcelona, Rome, Athens, and Istanbul, explore picturesque islands such as Santorini and Mykonos, and experience the charm of lesser-known ports. The Mediterranean provides a perfect blend of history, culture, and natural beauty that can make a 21-night cruise truly memorable.
Cruise Inquiry